Papers

2025
General Anesthesia in Early Infancy Accelerates Visual Cortical Development
Gabard-Durnam L, McCormick S , Underwood E, Tao A, Kim I, Coffman S, Benster L, Graziano M, Nelson C, Berde C, Cornelissen L, and Hensch T
PNAS PNAS
Neurodevelopment at 10 months and 2-3 years old after early and prolonged anaesthesia in infancy: General Anaesthesia & Brain Activity study (GABA) secondary analysis
Cornelissen L, Coffman S, Kim I, Underwood E, Tao A, Maloney M, Donado C, Lobo K, Nelson CA, Hensch TK, Gabard-Durnam LJ, and Berde C.
BJA Open . 2025 Mar 10:14:100383. doi: 10.1016/j.bjao.2025.100383. eCollection 2025 Jun. PubMed
Rapid and cumulative adult plasticity in the mouse visual cortex
Miyamoto H, Mazaki E, Makino Y, Fang Q, Hamada T, Handa Y and Hensch TK.
Front Neural Circuits . 2025 Feb 28:19:1537305. doi: 10.3389/fncir.2025.1537305. eCollection 2025 PubMed
2024
Sleep-sensitive dopamine receptor expression in male mice underlies attention deficits after a critical period of early adversity.
Makino Y, Hodgson NW, Doenier E, Serbin AV, Osada K, Artoni P, Dickey M, Sullivan B, Potter-Dickey A, Komanchuk J, Sekhon B, Letourneau N, Ryan ND, Trauth J, Cameron JL, Hensch TK.
Science Transl Med. 2024 Oct 9;16(768):eadh9763. doi: 10.1126/scitranslmed.adh9763. PubMed
An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function.
Kambali M, Li Y, Unichenko P, Feria Pliego JA, Yadav R, Liu J, McGuinness P, Cobb JG, Wang M, Nagarajan R, Lyu J, Vongsouthi V, Jackson CJ, Engin E, Coyle JT, Shin J, Hodgson NW, Hensch TK, Talkowski ME, Homanics GE, Bolshakov VY, Henneberger C, Rudolph U.
Mol Psychiatry. 2024 Aug 30. doi: 10.1038/s41380-024-02711-5. PubMed
Neurodevelopment of children exposed to prolonged anesthesia in infancy: GABA study interim analysis of resting-state brain networks at 2, 4, and 10-months old.
Desowska A, Coffman S, Kim I, Underwood E, Tao A, Lopez KL, Nelson CA, Hensch TK, Gabard-Durnam L, Cornelissen L, Berde CB.
Neuroimage Clin. 2024;42:103614. doi: 10.1016/j.nicl.2024.103614. PubMed
2023
Durable recovery from amblyopia with donepezil
Wu C, Gaier ED, Nihalani BR, Whitecross S, Hensch TK, Hunter DG.
Sci Rep. 2023; 13(1):10161. PubMed
Maximal Memory Capacity Near the Edge of Chaos in Balanced Cortical E-I Networks.
Kanamaru T, Hensch TK, Aihara K.
Neural Comput. 2023; 20 (1-33). PubMed
N-acetylcysteine treatment mitigates loss of cortical parvalbumin-positive interneuron and perineuronal net integrity resulting from persistent oxidative stress in a rat TBI model.
Hameed MQ, Hodgson N, Lee HHC, Pascual-Leone A, MacMullin PC, Jannati A, Dhamne SC, Hensch TK, Rotenberg A.
Cereb Cortex. 2023: 33(7):4070-4084. PubMed
Rapid synaptic and gamma rhythm signature of mouse critical period plasticity.
Quast KB, Reh RK, Caiati MD, Kopell N, McCarthy MM, Hensch TK.
Proc Natl Acad Sci U S A. 2023; 120(2):e2123182120. PubMed
2022
Tactile sensitivity and motor coordination in infancy: Effect of age, prior surgery, anaesthesia & critical illness.
Cornelissen L, Underwood E, Gabard-Durnam LJ, Soto M, Tao A, Lobo K, Hensch TK, Berde CB.
PLoS One. 2022; 17(12):e0279705. PubMed
Translating the Biology of Adversity and Resilience Into New Measures for Pediatric Practice.
Shonkoff JP, Boyce WT, Bush NR, Gunnar MR, Hensch TK, Levitt P, Meaney MJ, Nelson CA, Slopen N, Williams DR, Silveira PP.
Pediatrics. 2022; 149(6):e2021054493. PubMed
Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression.
Zhu Y, Wang MJ, Crawford KM, Ramírez-Tapia JC, Lussier AA, Davis KA, de Leeuw C, Takesian AE.
Neuropsychopharmacology. 2022; 47(2):497-506. PubMed
2021
Dynamical Characteristics of Wild-Type Mouse Spontaneous Pupillary Fluctuations.
Sviridova N, Artoni P, Fagiolini M, Hensch TK, Aihara K.
Annu Int Conf IEEE Eng Med Biol Soc. 2021:853-856. IEEE
α2-containing γ-aminobutyric acid type A receptors promote stress resiliency in male mice
Benham RS, Choi C, Hodgson NW, Hewage NB, Kastli R, Donahue RJ, Muschamp JW, Engin E, Carlezon WA Jr, Hensch TK, Rudolph U.
Neuropsychopharmacology. 2021; 46(12):2197-2206. PubMed
Distributional learning of speech sound categories is gated by sensitive periods.
Reh RK, Hensch TK, Werker JF.
Cognition. 2021; 213:104653. PubMed
“Scrap & build” functional circuits: Molecular and cellular basis of neural remodeling.
Emoto K, Hensch TK, Yuzaki M.
Neurosci Res. 2021;167:1-2 PubMed
Kv3.1 channels regulate the rate of critical period plasticity.
Matsuda YT, Miyamoto H, Joho RH, Hensch TK.
Neurosci Res. 2021;167:3-10. PubMed
2020
Increase in Seizure Susceptibility After Repetitive Concussion Results from Oxidative Stress, Parvalbumin-Positive Interneuron Dysfunction and Biphasic Increases in Glutamate/GABA Ratio.
MacMullin P, Hodgson N, Damar U, Lee HHC, Hameed MQ, Dhamne SC, Hyde D, Conley GM, Morriss N, Qiu J, Mannix R, Hensch TK, Rotenberg A.
Cereb Cortex. 2020; 30(12):6108-6120. PubMed
Critical period regulation across multiple timescales.
Reh RK, Dias BG, Nelson CA, Kaufer D, Werker JF,​ Kolb B, Levine JD, Hensch TK.
Proc Natl Acad Sci U S A. 2020, 22;117(38):23242-23251. PubMed
Single-nucleus RNA sequencing of mouse auditory cortex reveals critical period triggers and brakes.
Kalish BT, Barkat TR, Diel EE, Zhang EJ, Greenberg ME, Hensch TK.​
Proc Natl Acad Sci U S A. 2020, 117(21):11744-11752. PubMed
CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice.
Yamagata T, Raveau M, Kobayashi K, Miyamoto H, Tatsukawa T, Ogiwara I, Itohara S, Hensch TK, Yamakawa K.​
Neurobiol Dis. 2020 May 21;141:104954 PubMed
Reduced perceptual narrowing in synesthesia.
Maurer D, Ghloum JK, Gibson LC, Watson MR, Chen LM, Akins K, Enns JT, Hensch TK, Werker JF.
Proc Natl Acad Sci U S A. 2020;117(18):10089-10096 PubMed
2019
Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model.
Hameed MQ, Hsieh TH, Morales-Quezada L, Lee HHC, Damar U, MacMullin PC, Hensch TK, Rotenberg A.​
Cereb Cortex. 2019, 29(11):4506-4518. PubMed
Deep learning of spontaneous arousal fluctuations detects early cholinergic defects across neurodevelopmental mouse models and patients.
Artoni P, Piffer A, Vinci V, LeBlanc J, Nelson CA, Hensch TK, Fagiolini M.
Proc Natl Acad Sci U S A. 2019 Jul 22. PubMed
Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function.
McNair LF, Andersen JV, Aldana BI, Hohnholt MC, Nissen JD, Sun Y, Fischer KD, Sonnewald U, Nyberg N, Webster SC, Kapur K, Rimmele TS, Barone I, Hawks-Mayer H, Lipton JO, Hodgson NW, Hensch TK, Aoki CJ, Rosenberg PA, Waagepetersen HS.
J Neurosci. 2019;39(25):4847-4863. PubMed
Impaired cortico-striatal excitatory transmission triggers epilepsy.
Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K.
Nat Commun. 2019;10(1):1917. PubMed
Critical Period Regulation by Thyroid Hormones: Potential Mechanisms and Sex-Specific Aspects.
Batista G, Hensch TK.
Front. Mol. Neurosci., 05 April 2019. PubMed
Structural maturation of cortical perineuronal nets and their perforating synapses revealed by superresolution imaging.
Sigal YM, Bae H, Bogart LJ, Hensch TK, Zhuang X.
Proc Natl Acad Sci U S A. 2019;116(14):7071-7076. PubMed
NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity
Picard N, Takesian A, Fagiolini M, Hensch TK
Mol Psychiatry. 2019 Jan 29. doi: 10.1038/s41380-018-0341-9. [Epub ahead of print] PubMed
2018
Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.
Sun H, Takesian AE, Wang TT, Lippman-Bell JJ, Hensch TK, Jensen FE.
Cell Reports 2018 23(9): 2533-2540. PubMed
Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.
Ikuo Ogiwara et al.
Communications Biology. 2018;(96)2018 Nature
Inhibitory circuit gating of auditory critical-period plasticity.
Takesian AE, Bogart LJ, Lichtman JW, Hensch TK.
Nature Neuroscience. 2018 21(2): 218-227 PubMed
Critical periods in amblyopia.
Hensch TK and Quinlan EM
Vis Neurosci. 2018;Jan; 35: E014 PubMed
2017
Social Origins of Developmental Risk for Mental and Physical Illness.
Cameron JL, Eagleson KL, Fox NA, Hensch TK, Levitt P.
J. Neurosci. 2017 37(45): 10783-10791. PubMed
Chondroitin Sulfate is Required For Onset and Offset of Critical Period Plasticity in Visual Cortex.
Hou X, Yoshioka N, Tsukano H, Sakai A, et al.
Sci Rep, 2016; 7(1):12646 PubMed
Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.
Steullet P, Cabungcal JH, Coyle J, Didriksen M, Gill K, Grace AA, Hensch TK, LaMantia AS, Lindemann L, Maynard TM, Meyer U, Morishita H, O’Donnell P, Puhl M, Cuenod M, Do KQ.
Mol Psychiatry. 2017 Mar 21 doi: 10.1038/mp.2017.47 PubMed
Genetic Otx2 Mis-localization delays critical period plasticity across brain regions.
Lee HH, Bernard C, Ye Z, Acampora D, Simeon A, Prochiantz A, DeNardo AA, Hensch TK.
Mol Psychiatry, 2017; 1-9 PubMed
2016
Trajectory of Parvalbumin Cell Impairment and Loss of Cortical Inhibition in Traumatic Brain Injury
Hsieh T-H, Lee H, Hameed MQ, Pascual-Leone A, Hensch T, Rotenberg A.
Cerebral Cortex, 2016; 1-16 PubMed
The Power of the Infant Brain
Hensch, TK.
Scientific American. February 2016; 64-69. Audio
Restoration of Visual Function by Enhancing Conduction in Regenerated Axons.
Bei F, Lee H, Liu X, Gunner G, Jin H, Ma L, Wang C, Hou I, Hensch TK, Frank E, Sanes JR, Chen C, Fagiolini M, He Z.
Cell. 2016 Jan 14; 164: 219-232. Journal Link
2015
Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.
Lennartsson A, Arner E, Fagiolini M, Saxena A, Andersson R, Takahashi H, Noro Y, Sng J, Sandelin A, Hensch TK, Carninci P.
Epigenetics Chromatin. 2015; Dec 14;8:55. PubMed
Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.
Takei Y, Kikkawa YS, Atapour N, Hensch TK, Hirokawa N.
J Neurosci. 2015 Nov 25;35(47):15539-54. PubMed
Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons.
Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P.
Neuron. 2015 Nov 4; 88(3):475-483. Journal Link
Cell-specific regulation of NMDA receptor maturation by MECP2 in cortical circuits.
Mierau SB, Patrizi A, Hensch TK, Fagiolini M.
Biol Psychiatry. 2015 Jun 5. pii: S0006-3223(15)00467-9. PubMed
Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia.
Do KQ, Cuenod M, Hensch TK.
Schizophr Bull. 2015 Jun 1. pii: sbv065. [Epub ahead of print] PubMed
Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates.
Gurnot C, Martin-Subero I, Mah SM, Weikum W, Goodman SJ, Brain U, Werker JF, Kobor MS, Esteller M, Oberlander TF, Hensch TK.
Epigenetics. 2015 Apr 18:1-12. PubMed
Clock Genes Control Cortical Critical Period Timing.
Kobayashi Y, Ye Z, Hensch TK.
Neuron. 2015 Apr 8;86(1):264-75. PubMed
Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons.
Morishita H, Cabungcal JH, Chen Y, Do KQ, Hensch TK.
Biol Psychiatry. 2015 Jan 24. [Epub ahead of print] PubMed
Critical periods in speech perception: new directions.
Werker JF, Hensch TK.
Annu Rev Psychol. 2015 Jan 3;66:173-96. PubMed
2014
Sensory Integration in Mouse Insular Cortex Reflects GABA Circuit Maturation.
Gogolla N, Takesian AE, Feng G, Fagiolini M, Hensch TK.
Neuron. 2014 Aug 20;83(4):894-905. Neuron
Bistable parvalbumin circuits pivotal for brain plasticity.
Hensch TK.
Cell. 2014 Jan 16;156(1-2):17-9. PubMed
2013
Valproate reopens critical-period learning of absolute pitch.
Gervain J, Vines BW, Chen LM, Seo RJ, Hensch TK, Werker JF, Young AH.
Front. Syst. Neurosci., 2013 Dec 3 Frontiers
Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.
Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K.
Hum Mol Genet. 2013 Dec 1;22(23):4784-804. PubMed
Balancing plasticity/stability across brain development.
Takesian AE, Hensch TK.
Prog Brain Res. 2013;207:3-34. PubMed
Visual acuity development and plasticity in the absence of sensory experience.
Kang E, Durand S, Leblanc JJ, Hensch TK, Chen C, Fagiolini M.
J Neurosci. 2013 Nov 6;33(45):17789-96. PubMed
Germline recombination by conditional gene targeting with Parvalbumin-Cre lines
Kobayashi Y, Hensch TK.
Frontiers in Neural Circuits. 2013 October. PubMed
IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice
Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ebisui E, Ohshima T, Yamada T, Hensch TK, Hattori M, Mikoshiba1 K.
Frontiers in Neural Circuits. 2013 October. PubMed
A Theory of the Transition to Critical Period Plasticity: Inhibition Selectively Suppresses Spontaneous Activity.
Toyoizumi T, Miyamoto H, Yazaki-Sugiyama Y, Atapour N, Hensch TK, Miller KD.
Neuron. 2013 Oct 2; 80(1):51-63. PubMed
DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease.
Sanchez-Mut JV, Aso E, Panayotis N, Lott I, Dierssen M, Rabano A, Urdinguio RG, Fernandez AF, Astudillo A, Martin-Subero JI, Balint B, Fraga MF, Gomez A, Gurnot C, Roux JC, Avila J, Hensch TK, Ferrer I, Esteller M.
Brain. 2013 Oct;136(Pt 10):3018-27. PubMed
Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity.
Spatazza J, Lee HH, Di Nardo AA, Tibaldi L, Joliot A, Hensch TK, Prochiantz A.
Cell Reports. 2013 Jun 27;3(6):1815-23. PubMed
Perineuronal nets protect fast-spiking interneurons against oxidative stress.
Cabungcal JH, Steullet P, Morishita H, Kraftsik R, Cuenod M, Hensch TK, Do KQ.
Proc Natl Acad Sci U S A. 2013 May 28;110(22):9130-5. PubMed
2012
NMDA Receptor Regulation Prevents Regression of Visual Cortical Function in the Absence of Mecp2.
Durand S, Patrizi A, Quast KB, Hachigian L, Pavlyuk R, Saxena A, Carninci P, Hensch TK, Fagiolini M.
Neuron. 2012 Dec 20;76(6):1078-90. PubMed
A mouse model for too much TV?
Bilimoria PM, Hensch TK, Bavelier D.
Trends Cogn Sci. 2012 Nov;16(11):529-31. PubMed
Serotonergic Integration of Circadian Clock and Ultradian Sleep-Wake Cycles.
Miyamoto H, Nakamaru-Ogiso E, Hamada K, Hensch TK.
J Neurosci. 2012 Oct 17;32(42):14794-14803. PubMed
Critical period for acoustic preference in mice.
Yang EJ, Lin EW, Hensch TK.
Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17213-20. PubMed
Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception.
Weikum WM, Oberlander TF, Hensch TK, Werker JF.
Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17221-7. PubMed
Mouse with Na(v)1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment.
Ito S, Ogiwara I, Yamada K, Miyamoto H, Hensch TK, Osawa M, Yamakawa K.
Neurobiol Dis. 2012 Aug 16;49C:29-40. PubMed
Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex.
Beurdeley M, Spatazza J, Lee HH, Sugiyama S, Bernard C, Di Nardo AA, Hensch TK, Prochiantz A.
J Neurosci. 2012 Jul 4;32(27):9429-37. PubMed
Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain.
Saxena A, Wagatsuma A, Noro Y, Kuji T, Asaka-Oba A, Watahiki A, Gurnot C, Fagiolini M, Hensch TK, Carninci P.
Biotechniques. 2012 Jun;52(6):381-5. PubMed
Amblyopia: background to the special issue on stroke recovery.
Maurer D, Hensch TK.
Dev Psychobiol. 2012 Apr;54(3):224-38. PubMed
2011
A critical period for auditory thalamocortical connectivity.
Barkat TR, Polley DB, Hensch TK.
Nat Neurosci. 2011 Jul 31;14(9):1189-94. PubMed
Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex.
Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P.
Neuron. 2011 Feb 24;69(4):763-79. PubMed
Linking topography to tonotopy in the mouse auditory thalamocortical circuit.
Hackett TA, Barkat TR, O’Brien BM, Hensch TK, Polley DB.
J Neurosci. 2011 Feb 23;31(8):2983-95. PubMed
2010
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex.
Morishita H, Miwa JM, Heintz N, Hensch TK.
Science. 2010 Nov 26;330(6008):1238-40. PubMed
Removing brakes on adult brain plasticity: from molecular to behavioral interventions.
Bavelier D, Levi DM, Li RW, Dan Y, Hensch TK.
J Neurosci. 2010 Nov 10;30(45):14964-71. PubMed
2009
Bidirectional plasticity in fast-spiking GABA circuits by visual experience.
Yazaki-Sugiyama Y, Kang S, Câteau H, Fukai T, Hensch TK.
Nature. 2009 Nov 12;462(7270):218-21. PubMed
Common circuit defect of excitatory-inhibitory balance in mouse models of autism.
Gogolla N, Leblanc JJ, Quast KB, Südhof TC, Fagiolini M, Hensch TK.
J Neurodev Disord. 2009 Jun;1(2):172-81. PubMed
Development. Editorial overview.
Hensch TK, Brand AH.
Curr Opin Neurobiol. 2009 Apr;19(2):109-11. PubMed
From brain formation to plasticity: insights on Otx2 homeoprotein.
Sugiyama S, Prochiantz A, Hensch TK.
Dev Growth Differ. 2009 Apr;51(3):369-77. PubMed
Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility.
Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K.
Hum Mol Genet. 2009 Mar 15;18(6):1099-109. PubMed
2008
A resource for transcriptomic analysis in the mouse brain.
Plessy C, Fagiolini M, Wagatsuma A, Harasawa N, Kuji T, Asaka-Oba A, Kanzaki Y, Fujishima S, Waki K, Nakahara H, Hensch TK, Carninci P.
PLoS One. 2008 Aug 20;3(8):e3012. PubMed
Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity.
Sugiyama S, Di Nardo AA, Aizawa S, Matsuo I, Volovitch M, Prochiantz A, Hensch TK.
Cell. 2008 Aug 8;134(3):508-20. PubMed
Critical period revisited: impact on vision.
Morishita H, Hensch TK.
Curr Opin Neurobiol. 2008 Feb;18(1):101-7. PubMed
2007
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.
Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, Takeuchi T, Itohara S, Yanagawa Y, Obata K, Furuichi T, Hensch TK, Yamakawa K.
J Neurosci. 2007 May 30;27(22):5903-14. PubMed
Optimization of somatic inhibition at critical period onset in mouse visual cortex.
Katagiri H, Fagiolini M, Hensch TK.
Neuron. 2007 Mar 15;53(6):805-12. PubMed
2005
Excitatory-inhibitory balance and critical period plasticity in developing visual cortex.
Hensch TK, Fagiolini M.
Prog Brain Res. 2005;147:115-24. PubMed
International perspectives on engaging the public in neuroethics.
Illes J, Blakemore C, Hansson MG, Hensch TK, Leshner A, Maestre G, Magistretti P, Quirion R, Strata P.
Nat Rev Neurosci. 2005 Dec;6(12):977-82. PubMed
Critical period plasticity in local cortical circuits.
Hensch TK.
Nat Rev Neurosci. 2005 Nov;6(11):877-88. PubMed
Critical period mechanisms in developing visual cortex.
Hensch TK.
Curr Top Dev Biol. 2005;69:215-37. PubMed
Recovery in the blink of an eye.
Hensch TK.
Neuron. 2005 Oct 20;48(2):166-8. PubMed
The transcriptional landscape of the mammalian genome.
Carninci P, et al.
Science. 2005 Sep 2;309(5740):1559-63. PubMed
2004
Experience-dependent pruning of dendritic spines in visual cortex by tissue plasminogen activator.
Mataga N, Mizuguchi Y, Hensch TK.
Neuron. 2004 Dec 16;44(6):1031-41. PubMed
Critical period regulation.
Hensch TK.
Annu Rev Neurosci. 2004;27:549-79. PubMed
Specific GABAA circuits for visual cortical plasticity.
Fagiolini M, Fritschy JM, Löw K, Möhler H, Rudolph U, Hensch TK.
Science. 2004 Mar 12;303(5664):1681-3. PubMed
Columnar architecture sculpted by GABA circuits in developing cat visual cortex.
Hensch TK, Stryker MP.
Science. 2004 Mar 12;303(5664):1678-81.
2003
Reciprocal interaction of sleep and synaptic plasticity.
Miyamoto H, Hensch TK.
Mol Interv. 2003 Oct;3(7):404-17. PubMed
Subtraction of cap-trapped full-length cDNA libraries to select rare transcripts.
Hirozane-Kishikawa T, Shiraki T, Waki K, Nakamura M, Arakawa T, Kawai J, Fagiolini M, Hensch TK, Hayashizaki Y, Carninci P.
Biotechniques. 2003 Sep;35(3):510-6, 518. PubMed
Controlling the critical period.
Hensch TK.
Neurosci Res. 2003 Sep;47(1):17-22. PubMed
Rapid critical period induction by tonic inhibition in visual cortex.
Iwai Y, Fagiolini M, Obata K, Hensch TK.
J Neurosci. 2003 Jul 30;23(17):6695-702. PubMed
Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, et al.
Genome Res. 2003 Jun;13(6B):1273-89. PubMed
Experience-dependent slow-wave sleep development.
Miyamoto H, Katagiri H, Hensch T.
Nat Neurosci. 2003 Jun;6(6):553-4. PubMed
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling.
Fagiolini M, Katagiri H, Miyamoto H, Mori H, Grant SG, Mishina M, Hensch TK.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2854-9. PubMed
2002
Permissive proteolytic activity for visual cortical plasticity.
Mataga N, Nagai N, Hensch TK.
Proc Natl Acad Sci U S A. 2002 May 28;99(11):7717-21. PubMed
Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex.
Renger JJ, Hartman KN, Tsuchimoto Y, Yokoi M, Nakanishi S, Hensch TK.
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):1041-6. PubMed
2001
Experience-dependent plasticity of mouse visual cortex in the absence of the neuronal activity-dependent marker egr1/zif268.
Mataga N, Fujishima S, Condie BG, Hensch TK.
J Neurosci. 2001 Dec 15;21(24):9724-32. PubMed
2000
Inhibitory threshold for critical-period activation in primary visual cortex.
Fagiolini M, Hensch TK.
Nature. 2000 Mar 9;404(6774):183-6. PubMed
1999
Whisking away space in the brain.
Hensch TK.
Neuron. 1999 Nov;24(3):492-3. PubMed
1998
Local GABA circuit control of experience-dependent plasticity in developing visual cortex.
Hensch TK, Fagiolini M, Mataga N, Stryker MP, Baekkeskov S, Kash SF.
Science. 1998 Nov 20;282(5393):1504-8. PubMed
Comparison of plasticity in vivo and in vitro in the developing visual cortex of normal and protein kinase A RIbeta-deficient mice.
Hensch TK, Gordon JA, Brandon EP, McKnight GS, Idzerda RL, Stryker MP.
J Neurosci. 1998 Mar 15;18(6):2108-17. PubMed
1996
Ocular dominance plasticity under metabotropic glutamate receptor blockade.
Hensch TK, Stryker MP.
Science. 1996 Apr 26;272(5261):554-7. PubMed
Ocular dominance plasticity under metabotropic glutamate receptor blockade.
Hensch TK, Stryker MP.
Science. 1996 Apr 26;272(5261):554-7. PubMed
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.
Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, Jan YN.
Nature. 1996 Feb 29;379(6568):837-40. PubMed
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.
Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, Jan YN.
Nature. 1996 Feb 29;379(6568):837-40. PubMed