All Publications
Reviews & Commentaries
2015
Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.
Lennartsson A, Arner E, Fagiolini M, Saxena A, Andersson R, Takahashi H, Noro Y, Sng J, Sandelin A, Hensch TK, Carninci P.
Epigenetics Chromatin. 2015 Dec 14;8:55.
PubMed
Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.
Takei Y, Kikkawa YS, Atapour N, Hensch TK, Hirokawa N.
J Neurosci. 2015 Nov 25;35(47):15539-54.
PubMed
Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons.
Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P.
Neuron. 2015 Nov 4; 88(3):475-483.
Journal Link
Cell-specific regulation of NMDA receptor maturation by MECP2 in cortical circuits.
Mierau SB, Patrizi A, Hensch TK, Fagiolini M.
Biol Psychiatry. 2015 Jun 5. pii: S0006-3223(15)00467-9.
PubMed
Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates.
Gurnot C, Martin-Subero I, Mah SM, Weikum W, Goodman SJ, Brain U, Werker JF, Kobor MS, Esteller M, Oberlander TF, Hensch TK.
Epigenetics. 2015 Apr 18:1-12. [Epub ahead of print]
PubMed
Clock Genes Control Cortical Critical Period Timing.
Kobayashi Y, Ye Z, Hensch TK.
Neuron. 2015 March 19 [Epub ahead of print]
PubMed
Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons.
Morishita H, Cabungcal JH, Chen Y, Do KQ, Hensch TK.
Biol Psychiatry. 2015 Jan 24. [Epub ahead of print]
PubMed
2014
Sensory Integration in Mouse Insular Cortex Reflects GABA Circuit Maturation.
Gogolla N, Takesian AE, Feng G, Fagiolini M, Hensch TK.
Neuron. 2014 Aug 20;83(4):894-905. doi: 10.1016/j.neuron.2014.06.033.
PubMed
2013
Valproate reopens critical-period learning of absolute pitch.
Gervain J, Vines BW, Chen LM, Seo RJ, Hensch TK, Werker JF, Young AH.
Front. Syst. Neurosci., 2013 Dec 3 | doi: 10.3389/fnsys.2013.00102
Visual acuity development and plasticity in the absence of sensory experience.
Kang E, Durand S, Leblanc JJ, Hensch TK, Chen C, Fagiolini M.
J Neurosci. 2013 Nov 6;33(45):17789-96.
PubMed
Germline recombination by conditional gene targeting with Parvalbumin-Cre lines
Kobayashi Y, Hensch TK.
Frontiers in Neural Circuits. 2013 October.
PubMed
IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice
Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ebisui E, Ohshima T, Yamada T, Hensch TK, Hattori M, Mikoshiba1 K.
Frontiers in Neural Circuits. 2013 October.
PubMed
A Theory of the Transition to Critical Period Plasticity: Inhibition Selectively Suppresses Spontaneous Activity.
Toyoizumi T, Miyamoto H, Yazaki-Sugiyama Y, Atapour N, Hensch TK, Miller KD.
Neuron. 2013 Oct 2; 80(1):51-63.
PubMed
DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease.
Sanchez-Mut JV, Aso E, Panayotis N, Lott I, Dierssen M, Rabano A, Urdinguio RG, Fernandez AF, Astudillo A, Martin-Subero JI, Balint B, Fraga MF, Gomez A, Gurnot C, Roux JC, Avila J, Hensch TK, Ferrer I, Esteller M.
Brain. 2013 Oct;136(Pt 10):3018-27.
PubMed
Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.
Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K.
Hum Mol Genet. 2013 Dec 1;22(23):4784-804.
PubMed
Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity.
Spatazza J, Lee HH, Di Nardo AA, Tibaldi L, Joliot A, Hensch TK, Prochiantz A.
Cell Reports. Epub 2013 June 13.
PubMed
Perineuronal nets protect fast-spiking interneurons against oxidative stress.
Cabungcal JH, Steullet P, Morishita H, Kraftsik R, Cuenod M, Hensch TK, Do KQ.
Proc Natl Acad Sci U S A. 2013 May 28;110(22):9130-5.
PubMed
2012
NMDA Receptor Regulation Prevents Regression of Visual Cortical Function in the Absence of Mecp2.
Durand S, Patrizi A, Quast KB, Hachigian L, Pavlyuk R, Saxena A, Carninci P, Hensch TK, Fagiolini M.
Neuron. 2012 Dec 20;76(6):1078-90.
PubMed
Serotonergic Integration of Circadian Clock and Ultradian Sleep-Wake Cycles.
Miyamoto H, Nakamaru-Ogiso E, Hamada K, Hensch TK.
J Neurosci. 2012 Oct 17;32(42):14794-14803.
PubMed
Critical period for acoustic preference in mice.
Yang EJ, Lin EW, Hensch TK.
Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17213-20.
PubMed
Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception.
Weikum WM, Oberlander TF, Hensch TK, Werker JF.
Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17221-7.
PubMed
Mouse with Na(v)1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment.
Ito S, Ogiwara I, Yamada K, Miyamoto H, Hensch TK, Osawa M, Yamakawa K.
Neurobiol Dis. 2012 Aug 16;49C:29-40.
PubMed
Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex.
Beurdeley M, Spatazza J, Lee HH, Sugiyama S, Bernard C, Di Nardo AA, Hensch TK, Prochiantz A.
J Neurosci. 2012 Jul 4;32(27):9429-37.
PubMed
Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain.
Saxena A, Wagatsuma A, Noro Y, Kuji T, Asaka-Oba A, Watahiki A, Gurnot C, Fagiolini M, Hensch TK, Carninci P.
Biotechniques. 2012 Jun;52(6):381-5.
PubMed
2011
A critical period for auditory thalamocortical connectivity.
Barkat TR, Polley DB, Hensch TK.
Nat Neurosci. 2011 Jul 31;14(9):1189-94.
PubMed
Linking topography to tonotopy in the mouse auditory thalamocortical circuit.
Hackett TA, Barkat TR, O’Brien BM, Hensch TK, Polley DB.
J Neurosci. 2011 Feb 23;31(8):2983-95.
PubMed
Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex.
Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P.
Neuron. 2011 Feb 24;69(4):763-79.
PubMed
2010
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex.
Morishita H, Miwa JM, Heintz N, Hensch TK.
Science. 2010 Nov 26;330(6008):1238-40.
PubMed
2009
Bidirectional plasticity in fast-spiking GABA circuits by visual experience.
Yazaki-Sugiyama Y, Kang S, Câteau H, Fukai T, Hensch TK.
Nature. 2009 Nov 12;462(7270):218-21.
PubMed
Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility.
Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K.
Hum Mol Genet. 2009 Mar 15;18(6):1099-109.
PubMed
2008
A resource for transcriptomic analysis in the mouse brain.
Plessy C, Fagiolini M, Wagatsuma A, Harasawa N, Kuji T, Asaka-Oba A, Kanzaki Y, Fujishima S, Waki K, Nakahara H, Hensch TK, Carninci P.
PLoS One. 2008 Aug 20;3(8):e3012.
PubMed
Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity.
Sugiyama S, Di Nardo AA, Aizawa S, Matsuo I, Volovitch M, Prochiantz A, Hensch TK.
Cell. 2008 Aug 8;134(3):508-20.
PubMed
2007
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.
Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, Takeuchi T, Itohara S, Yanagawa Y, Obata K, Furuichi T, Hensch TK, Yamakawa K.
J Neurosci. 2007 May 30;27(22):5903-14.
PubMed
Optimization of somatic inhibition at critical period onset in mouse visual cortex.
Katagiri H, Fagiolini M, Hensch TK.
Neuron. 2007 Mar 15;53(6):805-12.
PubMed
2005
The transcriptional landscape of the mammalian genome.
Carninci P, et al.
Science. 2005 Sep 2;309(5740):1559-63.
PubMed
2004
Experience-dependent pruning of dendritic spines in visual cortex by tissue plasminogen activator.
Mataga N, Mizuguchi Y, Hensch TK.
Neuron. 2004 Dec 16;44(6):1031-41.
PubMed
Specific GABAA circuits for visual cortical plasticity.
Fagiolini M, Fritschy JM, Löw K, Möhler H, Rudolph U, Hensch TK.
Science. 2004 Mar 12;303(5664):1681-3.
PubMed
Columnar architecture sculpted by GABA circuits in developing cat visual cortex.
Hensch TK, Stryker MP.
Science. 2004 Mar 12;303(5664):1678-81.
PubMed
2003
Subtraction of cap-trapped full-length cDNA libraries to select rare transcripts.
Hirozane-Kishikawa T, Shiraki T, Waki K, Nakamura M, Arakawa T, Kawai J, Fagiolini M, Hensch TK, Hayashizaki Y, Carninci P.
Biotechniques. 2003 Sep;35(3):510-6, 518.
PubMed
Rapid critical period induction by tonic inhibition in visual cortex.
Iwai Y, Fagiolini M, Obata K, Hensch TK.
J Neurosci. 2003 Jul 30;23(17):6695-702.
PubMed
Experience-dependent slow-wave sleep development.
Miyamoto H, Katagiri H, Hensch T.
Nat Neurosci. 2003 Jun;6(6):553-4.
PubMed
Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, et al.
Genome Res. 2003 Jun;13(6B):1273-89.
PubMed
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling.
Fagiolini M, Katagiri H, Miyamoto H, Mori H, Grant SG, Mishina M, Hensch TK.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2854-9.
PubMed
2002
Permissive proteolytic activity for visual cortical plasticity.
Mataga N, Nagai N, Hensch TK.
Proc Natl Acad Sci U S A. 2002 May 28;99(11):7717-21.
PubMed
Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex.
Renger JJ, Hartman KN, Tsuchimoto Y, Yokoi M, Nakanishi S, Hensch TK.
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):1041-6.
PubMed
2001
Experience-dependent plasticity of mouse visual cortex in the absence of the neuronal activity-dependent marker egr1/zif268.
Mataga N, Fujishima S, Condie BG, Hensch TK.
J Neurosci. 2001 Dec 15;21(24):9724-32.
PubMed
2000
Inhibitory threshold for critical-period activation in primary visual cortex.
Fagiolini M, Hensch TK.
Nature. 2000 Mar 9;404(6774):183-6.
PubMed
1998
Local GABA circuit control of experience-dependent plasticity in developing visual cortex.
Hensch TK, Fagiolini M, Mataga N, Stryker MP, Baekkeskov S, Kash SF.
Science. 1998 Nov 20;282(5393):1504-8.
PubMed
Comparison of plasticity in vivo and in vitro in the developing visual cortex of normal and protein kinase A RIbeta-deficient mice.
Hensch TK, Gordon JA, Brandon EP, McKnight GS, Idzerda RL, Stryker MP.
J Neurosci. 1998 Mar 15;18(6):2108-17.
PubMed
1996
Ocular dominance plasticity under metabotropic glutamate receptor blockade.
Hensch TK, Stryker MP.
Science. 1996 Apr 26;272(5261):554-7.
PubMed
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.
Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, Jan YN.
Nature. 1996 Feb 29;379(6568):837-40.
PubMed
Hensch Lab 